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A rugged Big Ten slate has maybe taken the starch out of SC, which appeared tired in the second half of a heavy loss at Oregon on Saturday. Still, rare that 82-61 scoreline, as after going over 15-3 the preceding 18 games, the Trojans landed on the under side. Though they’re at least back at the Galen Center, where when last seen they were involved in a back-and-forth with Ohio State last Wednesday that landed 169 (87-82 Buckeyes). Note SC shot 64% from the floor when it won at Seattle on December 7 as Desmond Claude scored 20 as the Trojans looked a step quicker across the floor than the Huskies. Note U-Dub, struggling defensively, on a 7-2 over run into tonight. Play Washington-USC Over

Huskies offense is weak, and slow. I get all of this. But they’re over in 8 of 10 games. They are allowing 83/G in their last 7 road games (6-1 over). Those games average 155. First game between them went over. USC is over in 13 of 17, 15-5 over with 2-3 days off, 12-6 over at home. When total is 150.5 and up he’s 11-3 over. USC 6-2 over last 8 at home, averaging 157 points. Both bottom 5 D teams in Big 10, USC 2nd best in Big 10 from field, 2nd best from 3 land and WSH second-worst 3pt D in Big 10. USC 14-4 over in Big 10. USC under last game; have not gone under two in row all season.

The Big Ten slate has taken a toll on both of these Pac-12 refugees. For U-Dub, however, there’s not much left. Even a spot in the Big Ten Tourney looks out of the question after getting thumped by Indiana. Defense has really sagged lately for the Huskies, who have allowed 85 ppg in the current four-game skid. Meanwhile, the Trojans need to win to keep their Big Ten Tourney hopes within reach, and have looked tired themselves in a five-game skid. But SC did hit 64% from the floor and befuddled U-Dub with its quickness in Seattle back on December 7, when bolting to a 51-25 lead at the break en route to an 85-61 romp. Play USC.

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OPPONENT	W/L	ATS	ML	O/U
IND03/02/2025	78-62LOSS	+1.5LOSS	+110LOSS	144.5UNDER
@WISC02/26/2025	62-88LOSS	+13.5LOSS	+773LOSS	148.5OVER
@IOWA02/23/2025	79-85LOSS	+6.5WIN	+223LOSS	157.5OVER
RUT02/20/2025	89-85LOSS	-2.5LOSS	-139LOSS	147.5OVER
@PSU02/16/2025	75-73WIN	+6.0WIN	+213WIN	150.5UNDER

UW men blown out by USC in road finale

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Washington vs USC Odds, Picks, Predictions for Wednesday, March 5

Credit: Getty Images.

The Washington Huskies take on the USC Trojans in Los Angeles, CA. Tip-off is set for 10:30 p.m. ET on Big Ten Network.

USC is favored by 6.5 points on the spread with a moneyline of -310. The total is set at 150.5 points.

Here’s my Washington vs. USC predictions and college basketball picks for March 5, 2025.

My Pick: USC -8 or Better

My Washington vs USC best bet is on the Trojans spread, with the best odds currently available at DraftKings. For all of your college basketball bets, find the best lines using our live NCAAB odds page.

I’m laying the points with the Trojans.

I’m passing on the moneyline.

I’m passing on the over/under.

My Pick: USC -8 or Better

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While USC has lost five straight games, I still think the Trojans’ offense has trended up as the season has progressed.

Eric Musselman has messed with the lineups plenty, but the Desmond Claude-Wesley Yates III-Chibuzo Agbo-Saint Thomas-Rashaun Agee starting five has pieced together a respectable 119 Offensive Rating.

Although they lack spacing and shooting, the Trojans have become a good dribble offense (.90 pick-and-roll ball-handler PPP, 90th percentile, per Synergy).

Claude and Yates are excellent in that department, and the team is especially deadly in the mid-range (44% shooting on over eight attempts per game, 97th percentile, per CBB Analytics).

That feels like a good formula against Washington’s lackluster drop-coverage defense that funnels on-ball creation into the middle of the court and doesn’t do much to stop it (.82 pick-and-roll ball-handler PPP allowed, 35th percentile, per Synergy).

Washington parks Great Osobor at the rim, sticks on perimeter shooters and hands opposing ball-handlers lanes. However, the Huskies’ interior defense has regressed significantly since the Franck Kepnang injury, so they’re lifeless across the interior.

Unsurprisingly, the Trojans dropped 85 points in the first head-to-head meeting by shooting a ridiculous 25-for-34 (74%) from the interior. And they had no issues winning off the dribble (26 points on 24 ball-screens, 1.08 PPP, per Synergy).

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Washington Odds
Spread	Total	Moneyline
+6.5 -108	150.5 -112o / -108u	+250

USC Odds
Spread	Total	Moneyline
-6.5 -112	150.5 -112o / -108u	-310